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The treatment of aged rats with an inhibitor of iNOS or the use of GSNO in vitro demonstrated that SIRT1 is inhibited by S-nitrosylation and this results in p53 and NF-B increased activity with consequent production of pro-inflammatory cytokines [99]

Lipid droplets and associated proteins in sebocytes
Lonardo A, Lombardini S, Scaglioni F, et al
10.1111/cpr.12472 Cell Prolif

71 ZhangJ.XuQ.YangH

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