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The cause of FD remains to be established, but recent data suggest that infections, brain-gut disturbances, duodenal perturbations and food may play a crucial role in pathophysiology of FD (6)
& Marti-Cabrera, M
Majzoub A, Arafa M, Mahdi M, Agarwal A, Al Said S, Al-Emadi I, et al

Serum C-peptide, IGFBP-1 and IGFBP-2 and risk of colon and rectal cancers in the European Prospective Investigation into Cancer and Nutrition

It also protects pancreatic beta cells from oxidative damage, supporting natural insulin production

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