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Newton PT, Vuppalapati KK, Bouderlique T, Chagin AS

In inflammatory bowel diseases, garlic essential oil exerts antiinflammatory effects through dysregulation of IL10 and reduction of IL12, preventing IL12 from binding to its receptors on T and NK cells and, thus, inhibiting IFN production (Hodge et al., 2002)

There are other bands with higher (66 kDa, 97 kDa) and lower (30 kDa)molecular weights also detected besides the 42 kDa band indicating the proteolysis of GLUL protein by the ubiquitin system(PMID:10091759)

Acta Pharmacol Sin 41(4):471482 Krsser S, Marquet A, Gallemann D, Wolna P, Fauchoux N, Hermann R et al (2012) Effects of ketoconazole treatment on the pharmacokinetics of safinamide and its plasma metabolites in healthy adult subjects