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Description
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TMAO reduces bile acid pools, inhibiting FXR activity, disrupting bile acid-FXR signaling, and upregulating pathways worsening hepatic steatosis, as confirmed in HFD-fed C57BL/6J mice and human samples (154)
Eur Heart J 2019
L-carnitine plays an important role in transporting fatty acids to the mitochondria, the structures responsible for energy production in cells
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