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The F-box motif is located in the N-terminus of FBL2, followed by 11 leucine-rich repeats (Ilyin et al., 1999) and the CAAX motif, which is thought to be modified by geranylgeranylation (Wang et al., 2005a)

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Les modifications de conformation possiblement induites par le milieu ractionnel hydrophobe, notamment au niveau du lid , demeurent inconnues

30 There are several additional transcription factors that also function as cofactors of DAF-16
