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Description
These observations come from in vitro analysis and should be interpreted within a research context

doi: 10.1371/journal.pone.0045979

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Li et al., 2014)

These changes were found to be caused by endothelial cell dysfunction rather than a smooth muscle cell defect, as stimulation of mesenteric vessels with the NO donor sodium nitroprusside yielded the same vasodilatory response in CBS +/ and wildtype vessels

While more research is needed to confirm long-term outcomes, current evidence supports its use in supervised clinical settings
