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Pearsall, Sarah M

Androgen depletion causes AR gene and/or enhancer amplification, which renders AR more sensitive to lower levels of ligands, and induces somatic mutations that broaden ARs ligand-binding spectrum or turn antagonists into agonists [4, 26, 27]

Previous studies have attempted to compare the clinical characteristics of patients with WD

In addition, in this new article, there is a case report of a patient (Case 2, 26 years old) who had regression of the plaque in a significantly shorter time, most likely due to his younger age

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In adults, dermatomyositis is often associated with underlying malignancy but not in juvenile dermatomyositis, a distinct variant of this condition peaking at 8 years of age
