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The abnormal expression of GPx2 was detected in different tumors, and GPx2 was up-regulated in colorectal cancer [51, 52] and down-regulated in prostate intraepithelial neoplasia [53], suggesting that GPx2 plays complex roles in tumorigenesis [23]

68 Moreover, excessive ROS hyperphosphorylate Aurora A, disrupting spindle assembly, 69 and oxidize APC/C components like APC11, inhibiting cyclin B degradation and prolonging mitotic arrest

Influence of melatonin supplementation on serum antioxidative properties and impact of the quality of life in multiple sclerosis patients

Sekhar, R.V., McKay, S.V., Patel, S.G., Guthikonda, A.P., Reddy, V.T., Balasubramanyam, A

Additionally, photodynamic therapy enhances the anti-tumor immune response, augmenting the activation of tumor-specific immune cells [199]

The severity varies significantly based on individual factors such as gut health, dosage, and existing digestive sensitivities