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The term "Tokyo glutathione FDA approved" can be misleading

Li H, Liu X, Wang D, Su L, Zhao T, Li Z, Lin C, Zhang Y, Huang B, Lu J, Li X (2017) O-GlcNAcylation of SKN-1 modulates the lifespan and oxidative stress resistance in Caenorhabditis elegans

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It helps regenerate oxidized glutathione, thereby supporting its function as a potent antioxidant and detoxifier

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Hyperglycemia-Induced Overexpression of PH Domain Leucine-Rich Repeat Protein Phosphatase 1 (PHLPP1) Compromises the Cardioprotective Effect of Ischemic Postconditioning Via Modulation of the Akt/Mst1 Pathway Signaling