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[PubMed] [Wolters] Kennedy RH, Owings R, Shekhawat, N, Joseph, J
22,24 Also, the puncture point should not be made excessively deep, and if bleeding occurs, an alternative entry site slightly proximal to the original puncture should be selected

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Modulating effect of SIRT1 activation induced by Resveratrol on Foxo1-associated apoptotic signalling in senescent heart

And they're probably skirting that line a little bit