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Despite the widespread use of serotonergic medications, benzodiazepines and cognitive behavioral therapy (CBT), therapeutic outcomes remain limited with less than 50% of patients reaching full remission and nearly one-third do not respond to conventional treatments (De Vries et al., 2016)

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Comprising 83 amino acids, this compound features a crucial 13-amino acid extension at the N-terminus and a substitution of Arginine for Glutamic Acid at position 3

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[DOI] [PMC free article] [PubMed] [Google Scholar] Tang M, Gao G, Rueda CB, Yu H, Thibodeaux DN, Awano T, Engelstad KM, Sanchez-Quintero MJ, Yang H, Li F, Li H, Su Q, Shetler KE, Jones L, Seo R, McConathy J, Hillman EM, Noebels JL, De Vivo DC, Monani UR, 2017

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