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Gene expression on BDNF and SK-3 was quantified using real-time PCR, revealing that VPA reduced the expression BDNF, which plays a crucial role in synaptic plasticity and neuronal survival, and increased GSK-3, which is involved in neurodevelopment and neuroinflammation whereas crocin dose-dependently normalized both markers (Hosseini et al., 2025)

Sleep medications, which are sometimes prescribed for adults with insomnia, such as benzodiazepines or even antihistamines, can cause activation or agitation in some children and should be used with caution
Functions of the brain mitochondria in physiological conditions The human brain, which weight accounts for ~2% of the body weight, consumes 20% of the whole bodys oxygen

Presynaptic mitochondrial calcium sequestration influences transmission at mammalian central synapses
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