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Complications seen with diabetes range from heart disease (2 to 4 times higher occurence than in non-diabetics) to blindness, kidney disease, amputations, nerve damage and erectile dysfunction

Thus, if a drug is known to cause local mucosal irritation, it may be possible to find carriers that can deliver the drug without local side effects [134]

Marine-derived alternariol suppresses inflammation by regulating T cell activation and migration

The combination of ferroptosis inducers with TMZ produces synergistic killing effects, and GPX4 inhibitors such as RSL3 can significantly amplify the cytotoxic effects of TMZ

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