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Since few years, targeted therapies emerged as a promising senolytic approach, and several molecules are under clinical evaluation

The specific peptides now being studied in the context of PMOS each target a different part of this dysfunction some at the metabolic level, some at the hypothalamic level, some at the tissue level

Verdict at a Glance CagriSema demonstrates meaningfully greater weight loss than semaglutide alone (20.4% vs 14.9%), driven by the complementary amylin pathway from cagrilintide

And like such disorders, we will discuss recent evidence describing how progression of pathology throughout the CNS could be based on prion-like spread of proteopathic seeds

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