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2025 Mar 7;151(3):103

The zero withdrawal rate in AOD-9604 trials suggests excellent practical tolerability that extends beyond merely counting adverse events to assessing their real impact on treatment continuation

They look at the patients needs and health

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However, if extremely high doses are given for a long time, pyridoxine can cause nerve damage leading to numbness or tingling in the hands and feet (peripheral neuropathy)

Build stacks gradually over successive cycles
