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However, after the first decade of HTLV-1/2 screening in blood banks, a reduction in the prevalence of HTLV-1/2 occurred when comparing the REDS results with data from 1995 to 2000 in the Brazilian national seroprevalence study in blood centers, but done without the use of confirmatory testing and based on an EIA (4)

Indeed, a significantly lower glutathione-S-transferase (GST) enzyme activity and significantly high MDA levels have been shown in the cumulus cells of poor responders compared to high responders (220)

Histological analysis revealed reduced hepatocellular necrosis and inflammation in treated groups compared to controls

Statistical analysis of metabolomics data All visualization and significance testing of metabolomics was conducted using the MetaboAnalyst 5.0 package (Pang et al., 2021)

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& McKnight, S