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Blinding was not performed during animal experiments and data collection, but outcome assessments (e.g., IHC scoring) were conducted by blinded investigators

Daily dosing at 500mcg combined peptides exhausts one 2mL-reconstituted vial in 1819 days

Yanase F, Tosif SH, Churilov L, Yee K, Bellomo R, Gunn K, Kim C, Krizhanovskii C, Hahn RG, Riedel B, Weinberg L

The upregulated CD38 was also observed during the aging process, by secreted cytokines IL-6, interferons and soluble factors from senescent cells as part of so-called senescence-associated secretory phenotype (SASP) 21,27,36,47,48,49,50

Repetitive mild brain trauma accelerates Abeta deposition, lipid peroxidation, and cognitive impairment in a transgenic mouse model of Alzheimer amyloidosis