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Patients treated with eltrombopag did have higher platelet counts at the start of subsequent treatment cycles, but it did not reach the primary end point [36]

These results suggest a protective effect of testosterone on mitochondrial morphology in males

A d aily dose of 250mg has been shown to be effective in clinical studies [7]

doi: 10.1128/mBio.0004215 33 NiC.ChenY.XuY.ZhaoJ.LiQ.XiaoC.et al

Additionally, accumulation of free toxic compounds such as long chain fatty acid surrounding the mitochondria induces mitochondrial membrane permeability because of mitochondrial membrane depolarization and membrane canals formation