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It has been reported that the overexpression of hsa-let-7c can downregulate the renewal capacity of stem cells subsets, and the upregulation of expression of hsa-let-7c is related with the mechanism of GH/IGF-1 axis signaling pathway 16,17

292, C641C657

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Kojic acid gives visibly brighter skin by reducing excess melanin and mild oxidative stress

(2006) reported that upon activation of p38 MAPK due to the high levels of cytokines like iNOS, p38 MAPK was maintained at a hyper-phosphorylated state, the beta cells producing insulin was driven into apoptosis and eventually cell death