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Targeting p53 therapeutically could help reduce neuronal loss in PD [34]

[DOI] [PMC free article] [PubMed] [Google Scholar] 95.Farre J.C., Mahalingam S.S., Proietto M., Subramani S

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The disruption of this network produces organelle-specific imbalances that propagate into cellular dysfunction and contribute to a wide spectrum of human diseases, including neurodegeneration, cancer, metabolic disease and developmental disorders

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GNMT deficiency is inherited as an autosomal recessive disorder associated with hypermethioninemia, elevated serum SAM levels, and normal levels of sarcosine