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doi: 10.1186/s13075-017-1303-3 4 McInnesIBSchettG

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In a dose-dependent way, withaferin derivatives inhibit the ability of cancer cells to form colonies [107]

Interestingly, a study showed that the NF-kB pathway is intimately associated with thyroid cell survival and expression of key thyroid markers, such as thyroid peroxidase, and thyroglobulin, and is an essential transcription factor for maintenance of thyroid function 40

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More specifically, the researchers posited that the peptide may have enhanced the expression of Ki-67 and CD98hc that are less intensively synthesized during cell aging