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These include people who have had organ transplants, and those who are on immuno-suppressive therapies

10.1007/s00216-016-9533-9 128 XuL.HuangQ.TanX.ZhaoQ.WuJ.LiaoH.et al (2021)

10.1016/j.jpba.2017.05.010 46 RizzutiA.AlvarengaC.StockerG.FragaL.SantosH
Altogether, these results demonstrate significant bidirectional changes in productivity between adapted and non-adapted cultures and raise the possibility that changes in DNA methylation might underpin the observed phenotypic differences

For detection of 1-MNA, an early approach used an ion-pairing reagent to extract the positively charged and radioactive methylation product that can be measured using a scintillation counter

Annals of the New York Academy of Sciences, 1112(1), 112
