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Regularly evaluate patients for signs and symptoms of OIED (e.g., dysphagia, regurgitation, non-cardiac chest pain) and, if necessary, adjust opioid therapy as clinically appropriate (see CLINICAL PHARMACOLOGY)

However, this is the first demonstration of a human serum-derived educated spheroid system being used to prospectively confirm its predictive accuracy, which strengthens our confidence in its robustness
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However, any combination approach should be undertaken with medical supervision and careful monitoring of cumulative effects

The solvent choice, concentration, pH, and additives all require adjustment for nasal application

Romoser, T.D
