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Application of exogenous mixture of glutathione and stable isotope labeled glutathione for trapping reactive metabolites in cryopreserved human hepatocytes

10.1081/PFC-100107412 98 ShoaffJ

ATF3 promotes ferroptosis in sorafenib-induced cardiotoxicity by suppressing Slc7a11 expression

doi: 10.1007/s42452-024-06107-6 32 BehbahaniB

Reporter gene assay data suggests RUNX1 has a stronger suppressive effect on the minor rs2268277 allele (58)
Morphologically, ferroptosis is characterized by necrotic-like features, including loss of mitochondrial cristae, increased membrane density, outer membrane rupture, and reduced mitochondrial volume, while preserving plasma membrane integrity during early stages and maintaining normal nuclear morphology
