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doi: 10.1159/000339444 44 CarlAFaberJSteffensenRLaurbergPNygaardB

This effect was accompanied by downregulation of RAF and RAS mRNA and protein expression, suggesting a potential combinatorial therapeutic strategy (75)

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Impaired tubular epithelial cells can activate the innate immunity through pattern recognition receptors, and stimulate the secretion of several pro-inflammatory and chemokines, as well as recruitment of inflammatory cells to infiltrate the interstitium

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