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The metabolic pathways for GLN, arginine, isoleucine, tryptophan, cysteine, tyrosine, threonine, and L-serine play a crucial role in cancer

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doi: 10.1093/ajcn/nqaa215 240 ZappavignaS.CossuA

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The most important are the 78 kDa glucose regulatory protein (GRP78) and protein disulfide isomerase (PDI)

It is involved in many essential biochemical reactions as a co-enzyme and plays a primary role in the synthesis of proteins and the production of red blood cells