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This dynamic nature of TGF-s involvement implies that the timing of therapeutic intervention is critical

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This relationship has also shown that GSH depletion impairs dendritic cell mediated T-cell activation, further hindering immune response ( The glutaredoxin (Grx) system, another key player, operates in close association with the GSH pool and serves primarily to regulate protein thiol redox status through reversible de-glutathionylation

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6a), presumably due to the stabilization of the cytosolic loops by NADP + in the nap simulations (Fig