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RMD Open 2 , e000282 (2016)

However, SHBG also influences biological actions independent of total or free testosterone [117,118]

Magzal et al (61) found that hemodialysis patients exposed to oxidative stress had hypoalbuminemia and albumin modifications (the highest proportion of HNA1 in isolated albumin), and further revealed that these modifications triggered an inflammatory response in human umbilical vein endothelial cells (HUVEC) (Fig

doi: 10.4103/1673-5374.293145

, However, recent studies have suggested that, for methodological reasons, the level of hydrogen peroxide in aqueous humor was overestimated in these earlier studies