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j , Measurement of total glutathione levels in Pfa1 mock, FSP1 -expressing and FSP1 -expressing Gpx4 -knockout cells treated with or without BSO

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J Neurosci 25 : 57505756

Beyond its direct behavioral effects, recent research indicates that SFN may also influence gut microbiota composition, which plays a crucial role in the gut-brain axisa bidirectional communication pathway linking gastrointestinal health and neurological functioning

This review highlights the functional pathways and mechanisms, particularly gut microbe-induced chronic inflammation, protein misfolding, propagation of disease-specific pathology, defective protein clearance, and autoimmune dysregulation, linking gut microbial dysbiosis and neurodegeneration