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Moreover, treatment with antioxidants and ROS scavengers can sustainably reduce blood pressure in many experimental models of hypertension [245]

But lifestyle factors chip away at this defense

In a rat model of PD induced by 6-OHDA, 7-HMR treatment did not significantly prevent the loss of nigral dopaminergic neurons, but it produced notable anti-inflammatory effects in the brain (56)

References Ballatori N, Clarkson TW

Collectively, these findings underscore that boosting antioxidant capacity, particularly via the Nrf2 hub, is a validated strategy to mitigate the initial oxidative insult of I/R

Role of phenolic compounds in human disease: Current knowledge and future prospects