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Incomplete elimination of viral genomes is associated with chronic inflammation in nonhuman primate livers after AAV-mediated gene transfer
The first time an invader, like a virus or bacteria, enters your body, your immune system needs to look for the right tools (specific B-cells) to recognize the antigen and destroy the pathogen it belongs to
Although systemic fibrosis and encephalopathy are rare, they can be catastrophic
Trends Pharmacol Sci (2020) 41(2):12338
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Functional cure may not translate to complete cure because of the viral genome fragments that persist in the host cells
