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After multiple once daily dosing of divalproex sodium ER, the peak-to-trough fluctuation in plasma valproate concentrations was 10-20% lower than that of regular divalproex sodium given b.i.d., t.i.d., or q.i.d
In addition, biosynthetic pathways of the main groups of these compounds have been shortly described
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This oxidative stress disrupts mitochondrial regulation and activates vital inflammatory signaling pathways, such as NF-B and JAK/STAT
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