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Schlothauer, T

After stopping dexamethasone therapy, IR will fall

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Cuproptosis is a copper-dependent form of RCD driven by copper binding to lipoylated proteins in the TCA cycle, triggering a toxic ROS burst via Fenton-like reactions that amplify mitochondrial damage [6775]
These molecular actors collectively orchestrate an intracellular redox imbalance, culminating in the cells demise