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175 (7), 17801795.e19

Statistical analysis All data were statistically analyzed using GraphPad Prism 9.5.1 software and expressed as mean standard error of the mean (SEM)

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This has been shown to result in decreased production of pro-inflammatory cytokines such as Tumor Necrosis Factor alpha (TNF-), interleukin 6 (IL-6), interleukin 8 (IL-8), and interferon gamma (IFN-), and inflammation markers such as cyclooxygenase 2 (COX2) 26,45

Its influence extends to ameliorating microcirculatory disturbances seen in bone necrosis [1] and positively adjusting serum physiological markers, including total antioxidant capacity and lactate dehydrogenase [14], alongside inflammatory markers like the erythrocyte sedimentation rate [13]