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Interestingly, loss of intracellular hydrogen peroxide or lipid hydroperoxides by overexpression of catalase or GPx-4, respectively, inhibits cell cycle progression from G 0 /G 1 - to S-phase (278, 377)

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Our case, similarly to others mentioned above, puts into evidence the potential pulmonary toxicity of this drug, fortunately with a good clinical evolution under chemotherapy discontinuation

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