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Although the addition of CTP restored CTP levels in the CTPS1-KO cells, DNA repair efficiency was not restored to basal levels, indicating that the role of CTPS1 in the DDR is independent of CTP synthesis activity (Extended Data Fig

Primary dermal fibroblasts were collected from the dermis that was incubated with collagenase 035% (Gibco

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the highest level of grouping in the Medical Dictionary for Regulatory Activities (MedDRA) terminology) level

NSAIDs may increase the risk of thrombosis and acute renal failure in patients with COVID-19 infection

Next, we detected the levels of DCFH-DA and found that, compared to control cells, the ROS levels were significantly higher in ACTL6A-KD cells with or without H 2 O 2 treatment (Fig