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Smart nanomaterials for microbiome-targeted therapy Nanomaterials possess unique features such as high surface area-to-volume ratio, tunable surface chemistry, and controlled release properties, making them powerful tools in infection control and microbiome-targeted therapies

SchwingenschuhPKatschnigPEdwardsMJTeoJTKorliparaLVRothwellJCet al

But beneath the hype and fear is a simple story: these drugs target a core metabolic signaling pathway that influences cardiovascular health, inflammation, cognition, kidney function, and long-term resilience

[DOI] [PMC free article] [PubMed] [Google Scholar] 140.Dany M., Gencer S., Nganga R., Thomas R.J., Oleinik N., Baron K.D., Szulc Z.M., Ruvolo P., Kornblau S., Andreeff M., et al

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Indeed, human patients with -thalassemia show increased flow-mediated dilation without differences in anemia or hemolysis, suggesting that -globin control of vascular tone is a conserved mechanism from mouse to human (121)
