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GGT has multiple functions, including catalytic transfer of -glutamyl groups to amino acids and short peptides, hydrolysis of GSH to glutamyl moiety and cysteinyl glycine, and catabolism of GSH conjugates [31]

Cellular glutathione and thiols metabolism

Glutathione depletion is a major determinant of inhaled naphthalene respiratory toxicity and naphthalene metabolism in mice

Activation of NF-k antagonizes programmed cell death induced by TNFR1, and GSH depletion has been shown to down-regulate TNF-induced NF-k activation and sensitize to apoptotic cell death [123]

It is the regime associated with these substances which is fraught with problems

The first study was a randomized, double-blind study with 50 participants