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Description
G., & Freeman, R
Bioinformatics 25 , 14221423 (2009)
"Ethyl (2S)-2-[[1-[(4-fluorophenyl)methyl]indazole-3-carbonyl]amino]-3-methylbutanoate"
A #14 mutant with significantly higher glutathione content was isolated via acrolein resistance screening
In a Phase 2a trial, GSBR-1290 resulted in a significant weight loss of 6.2% after 12 weeks, outperforming the placebo group
However, electrochemical methods are marred with major obstacles, including the complex composition of the extracted mixtures, leading to electrode fouling [78]
