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The expression of melanogenesis-related genes and proteins, such as TYR, TRP-1, and TRP-2, as well as the microphthalmia-related transcription factor (MITF), was significantly suppressed by LEVs

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Its transcription is regulated by NRF2 and system X c inhibition

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Fuso A, Cavallaro RA, Zampelli A, et al

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