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In renal injury models, metformin can restore the transcriptional level of PGC-1, regulate mitochondrial viability and dynamics, and alleviate RF [56]

doi: 10.1038/s43018-023-00532-z

It only becomes relevant if you're using a topical DHT-inhibitor formulation, in which case check that product for DMSO before combining it in the same application

Sciex Analyst software version 1.6 was used for data acquisition

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