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Safety considerations were included using keywords such as (safety OR microbial contamination OR pathogens OR foodborne infections OR zoonotic risk)

Primary studies on construction and evaluation of ion-sensitive in situ gel loaded with paeonol-solid lipid nanoparticles for intranasal drug delivery

As early as 2004, a study identified iron deposition in the basal ganglia in a rat model of ICH (Nakamura et al., 2004)

Misawa A, Takayama K, Urano T, Inoue S

doi: 10.1186/1471-227X-4-3

10.1104/pp.107.101436 77 MittlerR.VanderauweraS.GolleryM.BreusegemF.Van BreusegemF