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In conclusion, to counteract the tentative theoretical concerns about BPC 157s complexity and multiple biological interactions, the extensive evidence provided by existing studies strongly supports the peptides safety and efficacy in resolving severe and multifactorial health issues without causing adverse effects [3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21,22,23,24,27,28,29,30,31,32,34,37,39,40]
However, at higher concentrations, monovalent or low-affinity antibodies are generally more effective for brain uptake, as they avoid the endocytic limitations associated with receptor crosslinking [279]

Med Genet 58 , 110 (2015)
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Kumar P, Sharma A
Physiol Entomol