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While selenium deficiency is a major etiological factor of Keshan disease (54), the seasonal and annual variation in disease occurrence suggested that other factors, especially an infectious agent, might be involved in addition to selenium deficiency (55)

Beyond their antioxidant function, GPx enzymes are involved in various biological processes, including post-translational protein modifications and cellular signaling [8]

Concluding remarks This article briefly reviewed the causes and manifestations of various liver diseases, including ALD, MASLD/MASH, TAFLD, and DILI

Pharmacologic inhibition of this enzyme with statins is actually the primary treatment for hypercholesterolemia

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