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1 Small apolipoprotein B (ApoB)-containing lipoproteins can cross the vascular endothelial barrier and accumulate in the arterial wall, leading to atheromatous plaque formation which is a precursor to subsequent blood vessel blockage and the clinical sequelae of myocardial infarction, stroke or other vascular disease

CRP : Assesses severity of inflammation

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D., Manchare, A., Nangare, S

In PD, therefore, we have a preponderance of profibrotic factors causing excessive deposition of collagen and ECM