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Yet, we have also seen that a physiological decrease occurs with advancing age

Evolution doesn't work that way
doi: 10.1111/imr.12903

Vitamin A modulates the expression of genes involved in iron bioavailability

In fertility, it can damage eggs, sperm, and embryos, diminishing quality and decreasing the likelihood of conception

Binding of immunoglobulins to protein A and immunoglobulin levels in mammalian sera