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Abnormal production and release of these mediators from mast cells can further exacerbate SARS-CoV-2-induced inflammation in the respiratory system

Acute and bilateral blindness due to optic neuropathy associated with copper deficiency

A distinctive pathological feature of ALS is the mislocalization and aggregation of phosphorylated TDP-43 (pTDP-43), a nuclear RNA-binding protein encoded by TARDBP

Additionally, bile acids released by the gallbladder activate receptors in the gut called bile acid-activated nuclear receptors

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