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Future Perspectives To sum up, it is generally believed that IGF1 enhances mitochondrial function by promoting both mitochondrial biogenesis and mitophagy under several conditions of metabolic or mitochondrial stress

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It is evident that dysregulation of the Nrf2 pathway and regulation of the inflammatory response and ferroptosis play key roles in the pathogenesis of several lung diseases, making Nrf2 a potential therapeutic target

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