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Una carenza di carnitina compromette gravemente la capacit del corpo di ossidare gli acidi grassi, portando a conseguenze che possono essere serie, in particolare a livello muscolare e cardiaco: debolezza muscolare : incapacit di generare energia sufficiente dal grasso, con conseguente debolezza e affaticamento muscolare (miopatia)

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These reactive aldehydes further disrupt mitochondrial function, activate pro-inflammatory pathways (e.g., NF-B), and sensitize nociceptive neurons, contributing to neuroinflammation, neuronal dysfunction in FM ( Mitochondrial dysfunction in FM is evident from reduced electron transport chain (ETC) activity, lower oxygen consumption in muscle biopsies, and diminished bioenergetic reserve ( Neuronal and microglial mitochondrial dysfunction in FM impairs electron transport chain (ETC) activity, leading to electron leakage and superoxide (O ) formation, which contribute to ATP deficits

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Dietary compounds are also closely linked to migraine occurrence