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Analysis showed that irisin inhibited -synuclein aggregation and enhanced the expression of brain-derived neurotrophic factor (BDNF) and peroxisome proliferator-activated receptor gamma coactivator 1 (PGC-1)

and at least one immunomodulatory marker analyzed

Vitamin C is a crucial component of both the innate (nonspecific) and adaptive (specific) portions of the immune system [18]

Especially in younger children, an irregular polymorphous hypersynchronous activity, sometimes resembling hypsarrhythmia may be recorded

doi: 10.3389/fnut.2026.1773391 Received 22 December 2025 Revised 16 January 2026 Accepted 21 January 2026 Published 04 February 2026 Volume 13 - 2026 Edited by Chenghao Lv, Central South University, China Reviewed by David Pei-Cheng Lin, Chung Shan Medical University, Taiwan Mohd Aizuddin Mohd Lazaldin, University Technology Malaysia, Malaysia Updates Copyright 2026 Cen, Li, Reilly, Chen, Jiang and Shu